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What is PRF and how does it work?

Platelet-rich fibrin (PRF), a patient-blood-derived living biomaterial, is becoming increasingly popular when it comes to the promotion of overall skin health. In more general terms, we are able to take a few vials of the patient’s blood from a simple blood draw and spin it down in a centrifuge, and then extract and utilize several growth elements. PRF is known for its ability to stimulate collagen production, tighten loose skin, add volume back to the face, and promote hair rejuvenation. By injecting PRF, an inflammatory response is created to kick start new cell growth. PRF injections have less of a risk for adverse effects because it is made up of the patient’s own blood. 

How is PRF used?

PRF can be used in many different ways for various amounts of concerns. PRF can be used alone in an injection or in combination with other aesthetic procedures such as microneedling. Microneedling with PRF is non-invasive and requires no downtime. You are able to see improvements in overall texture and tone by decreasing acne scars, under-eye bags, and brown spots. Microneedling is already a fan favorite here at GFaceMD, especially during the fall and winter seasons. If you are unfamiliar with the microneedling process, the treatment consists of tiny microscopic wounds made in the skin by sterile medical-grade needles. These microscopic wounds do not damage the skin but they do cause the skin to start the natural healing process. During this process, circulation is increased, and collagen is stimulated causing a beautiful result of more youthful skin.

PRF is also well known when it comes to under eye treatment. As we know, the under-eye area is known for showing signs of aging first. PRF can enhance the results of under eye filler. It can be used alone or in combination with filler to tighten loose skin, and improve under-eye dark circles. This same idea can be applied to many areas of the face where you can place PRF and filler in combination for best results. 

How are PRP and PRF different?

Although PRF is used to treat many of the same concerns as platelet-rich plasma (PRP), PRF releases growth factors for a much longer time. These growth factors are what stimulate cells to improve collagen and elastin to the skin. Both PRF and PRP require blood to be taken from the patient and placed in a centrifuge where the blood is processed. PRF is spun at a slower speed so that the layers of the blood do not separate as distinctly, allowing some of the white blood cells and stem cells to remain within the platelet layer. Another distinct difference is that PRP is placed in test tubes with an anticoagulant to keep the blood product from clotting. The PRF test tubes do not contain any anticoagulants making the platelet product as natural as possible. The clot formation that happens within the tubing of the PRF creates a spongy fibrin matrix that allows for the slow release of growth factors. 

Keep an eye out for one of our newest GFaceMD treatments! Just in time for fall, PRF will be added to our list of procedures to be injected alone or in combination with some of our favorites. 

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